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Dynamics of Methylated Cytosine Flipping by UHRF1
DNA methylation patterns, which are critical for gene expression, are replicated by DNA methyltransferase 1 (DNMT1) and ubiquitin-like containing PHD and RING finger domains 1 (UHRF1) proteins. This replication is initiated by the recognition of hemimethylated CpG sites and further flipping of methy...
Gardado en:
| Publicado en: | J Am Chem Soc |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5335914/ https://ncbi.nlm.nih.gov/pubmed/28112929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b00154 |
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