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Analysis of mtDNA/nDNA ratio in mice
The mitochondrial DNA (mtDNA) lacks a protection provided by the nucleosomes in the nuclear DNA and does not have a DNA repair mechanism, making it highly susceptible to damage, which can lead to mtDNA depletion. MtDNA depletion compromises the efficient function of cells and tissues and thus impact...
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| Publicado no: | Curr Protoc Mouse Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5335900/ https://ncbi.nlm.nih.gov/pubmed/28252199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpmo.21 |
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