Human Dendritic Cells Mitigate NK-Cell Dysfunction Mediated by Nonselective JAK1/2 Blockade

Janus kinase (JAK) inhibitors have achieved positive responses in myeloproliferative neoplasms, but at the expense of decreased natural killer (NK) cell numbers and compromised function. Selective JAK2 inhibition may also have a role in preventing and treating graft-vs-host disease after allogeneic...

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Detaylı Bibliyografya
Yayımlandı:Cancer Immunol Res
Asıl Yazarlar: Curran, Shane A., Shyer, Justin A., St. Angelo, Erin T., Talbot, Lillian R., Sharma, Sneh, Chung, David J., Heller, Glenn, Hsu, Katharine C., Betts, Brian C., Young, James W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335862/
https://ncbi.nlm.nih.gov/pubmed/27923824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0233
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