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The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs

A controlled inflammatory response is required for protection against infection, but persistent inflammation causes tissue damage. Dendritic cells (DCs) have a unique capacity to promote both inflammatory and anti-inflammatory processes. One key mechanism involved in DC-mediated immunosuppression is...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Salazar, Fabián, Awuah, Dennis, Negm, Ola H., Shakib, Farouk, Ghaemmaghami, Amir M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335671/
https://ncbi.nlm.nih.gov/pubmed/28256612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43337
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