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Cholesterol depletion impairs contractile machinery in neonatal rat cardiomyocytes

Cholesterol regulates numerous cellular processes. Depleting its synthesis in skeletal myofibers induces vacuolization and contraction impairment. However, little is known about how cholesterol reduction affects cardiomyocyte behavior. Here, we deplete cholesterol by incubating neonatal cardiomyocyt...

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書目詳細資料
發表在:Sci Rep
Main Authors: Hissa, Barbara, Oakes, Patrick W., Pontes, Bruno, Ramírez-San Juan, Guillermina, Gardel, Margaret L.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335656/
https://ncbi.nlm.nih.gov/pubmed/28256617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43764
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