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Cholesterol Depletion Alters Cardiomyocyte Subcellular Signaling and Increases Contractility

Membrane cholesterol levels play an important factor in regulating cell function. Sarcolemmal cholesterol is concentrated in lipid rafts and caveolae, which are flask-shaped invaginations of the plasma membrane. The scaffolding protein caveolin permits the enrichment of cholesterol in caveolae, and...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Haque, Mohammed Z., McIntosh, Victoria J., Abou Samra, Abdul B., Mohammad, Ramzi M., Lasley, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956108/
https://ncbi.nlm.nih.gov/pubmed/27441649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154151
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