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Macrophage LTB(4) drives efficient phagocytosis of Borrelia burgdorferi via BLT1 or BLT2

Unresolved experimental Lyme arthritis in C3H 5-lipoxygenase (5-LOX)(−/−) mice is associated with impaired macrophage phagocytosis of Borrelia burgdorferi. In the present study, we further investigated the effects of the 5-LOX metabolite, leukotriene (LT)B(4) on phagocytosis of B. burgdorferi. Bone...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Lipid Res
Prif Awduron: Zhang, Yan, Olson, Rachel M., Brown, Charles R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335579/
https://ncbi.nlm.nih.gov/pubmed/28053185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M068882
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