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Macrophage LTB(4) drives efficient phagocytosis of Borrelia burgdorferi via BLT1 or BLT2

Unresolved experimental Lyme arthritis in C3H 5-lipoxygenase (5-LOX)(−/−) mice is associated with impaired macrophage phagocytosis of Borrelia burgdorferi. In the present study, we further investigated the effects of the 5-LOX metabolite, leukotriene (LT)B(4) on phagocytosis of B. burgdorferi. Bone...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Autores principales: Zhang, Yan, Olson, Rachel M., Brown, Charles R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335579/
https://ncbi.nlm.nih.gov/pubmed/28053185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M068882
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