Myocyte-Derived Hsp90 Modulates Collagen Upregulation via Biphasic Activation of STAT-3 in Fibroblasts during Cardiac Hypertrophy

Signal transducer and activator of transcription 3 (STAT-3)-mediated signaling in relation to upregulated collagen expression in fibroblasts during cardiac hypertrophy is well defined. Our recent findings have identified heat shock protein 90 (Hsp90) to be a critical modulator of fibrotic signaling...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Datta, Ritwik, Bansal, Trisha, Rana, Santanu, Datta, Kaberi, Datta Chaudhuri, Ratul, Chawla-Sarkar, Mamta, Sarkar, Sagartirtha
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335508/
https://ncbi.nlm.nih.gov/pubmed/28031326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00611-16
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