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Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway

Myocardial hypertrophy, an inflammatory condition of cardiac muscles is a maladaptive response of the heart to biomechanical stress, hemodynamic or neurohormonal stimuli. Previous studies indicated that knockout of Arginyltransferase (ATE1) gene in mice and embryos leads to contractile dysfunction,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Singh, Kanika, Gupta, Ankit, Sarkar, Ashish, Gupta, Ishita, Rana, Santanu, Sarkar, Sagartirtha, Khan, Sameena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969214/
https://ncbi.nlm.nih.gov/pubmed/31953451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57379-7
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