The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling

The dry (nonneovascular) form of age‐related macular degeneration (AMD), a leading cause of blindness in the elderly, has few, if any, treatment options at present. It is characterized by early accumulation of cellular waste products in the retinal pigmented epithelium (RPE); rejuvenating impaired l...

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Publicado no:Aging Cell
Main Authors: Shang, Peng, Valapala, Mallika, Grebe, Rhonda, Hose, Stacey, Ghosh, Sayan, Bhutto, Imran A., Handa, James T., Lutty, Gerard A., Lu, Lixia, Wan, Jun, Qian, Jiang, Sergeev, Yuri, Puertollano, Rosa, Zigler, J. Samuel, Xu, Guo‐Tong, Sinha, Debasish
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334531/
https://ncbi.nlm.nih.gov/pubmed/28083894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12561
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