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βA3/A1-crystallin is required for proper astrocyte template formation and vascular remodeling in the retina

Nuc1 is a spontaneous rat mutant resulting from a mutation in the Cryba1 gene, coding for βA3/A1-crystallin. Our earlier studies with Nuc1 provided novel evidence that astrocytes, which express βA3/A1-crystallin, have a pivotal role in retinal remodeling. The role of astrocytes in the retina is only...

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Detalhes bibliográficos
Main Authors: Sinha, Debasish, Valapala, Mallika, Bhutto, Imran, Patek, Bonnie, Zhang, Cheng, Hose, Stacey, Yang, Fang, Cano, Marisol, Stark, Walter J., Lutty, Gerard A., Zigler, J. Samuel, Wawrousek, Eric F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773944/
https://ncbi.nlm.nih.gov/pubmed/22427112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-012-9608-0
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