Phenotypic characteristics of aged CD4(+) CD28(null) T lymphocytes are determined by changes in the whole‐genome DNA methylation pattern

Aging is associated with a progressive loss of the CD28 costimulatory molecule in CD4(+) lymphocytes (CD28(null) T cells), which is accompanied by the acquisition of new biological and functional properties that give rise to an impaired immune response. The regulatory mechanisms that govern the appe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Suarez‐Álvarez, Beatriz, Rodríguez, Ramón M., Schlangen, Karin, Raneros, Aroa Baragaño, Márquez‐Kisinousky, Leonardo, Fernández, Agustín F., Díaz‐Corte, Carmen, Aransay, Ana M., López‐Larrea, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334526/
https://ncbi.nlm.nih.gov/pubmed/28026094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12552
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados