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Toll-Like Receptor Ligand-Based Vaccine Adjuvants Require Intact MyD88 Signaling in Antigen-Presenting Cells for Germinal Center Formation and Antibody Production

Vaccines are critical in the fight against infectious diseases, and immune-stimulating adjuvants are essential for enhancing vaccine efficacy. However, the precise mechanisms of action of most adjuvants are unknown. There is an urgent need for customized and adjuvant formulated vaccines against immu...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mosaheb, Munir M., Reiser, Michael L., Wetzler, Lee M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334362/
https://ncbi.nlm.nih.gov/pubmed/28316602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00225
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