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Protease-activated receptor 1 contributes to angiotensin II-induced cardiovascular remodeling and inflammation

BACKGROUND: Angiotensin II (Ang II) plays an important role in cardiovascular disease. It also leads to the activation of coagulation. The coagulation protease thrombin induces cellular responses by activating protease activated receptor 1 (PAR-1). We investigated if PAR-1 contributes to Ang II-indu...

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Publicado en:Cardiology
Main Authors: Antoniak, Silvio, Cardenas, Jessica C., Buczek, Laura J., Church, Frank C., Mackman, Nigel, Pawlinski, Rafal
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334284/
https://ncbi.nlm.nih.gov/pubmed/27880950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000452269
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