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Protease-activated receptor 1 contributes to angiotensin II-induced cardiovascular remodeling and inflammation

BACKGROUND: Angiotensin II (Ang II) plays an important role in cardiovascular disease. It also leads to the activation of coagulation. The coagulation protease thrombin induces cellular responses by activating protease activated receptor 1 (PAR-1). We investigated if PAR-1 contributes to Ang II-indu...

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Bibliografske podrobnosti
izdano v:Cardiology
Main Authors: Antoniak, Silvio, Cardenas, Jessica C., Buczek, Laura J., Church, Frank C., Mackman, Nigel, Pawlinski, Rafal
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334284/
https://ncbi.nlm.nih.gov/pubmed/27880950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000452269
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