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Neuroimaging abnormalities in clade C HIV are independent of Tat genetic diversity

Controversy remains regarding the neurotoxicity of clade C human immunodeficiency virus (HIV-C). When examined in preclinical studies, a cysteine to serine substitution in the C31 dicysteine motif of the HIV-C Tat protein (C31S) results in less severe brain injury compared to other viral clades. By...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Paul, Robert H., Phillips, Sarah, Hoare, Jacqueline, Laidlaw, David H., Cabeen, Ryan, Olbricht, Gayla R., Su, Yuqing, Stein, Dan J., Engelbrecht, Susan, Seedat, Soraya, Salminen, Lauren E., Baker, Laurie M., Heaps, Jodi, Joska, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334278/
https://ncbi.nlm.nih.gov/pubmed/27913960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-016-0503-y
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