Impact of the HIV Tat C30C31S dicysteine substitution on neuropsychological function in patients with clade C disease

Previous animal studies have identified a C31S residue substitution in the C30C31 dicysteine motif of the Tat protein that is associated with reduced neurovirulence in clade C HIV. However, clinical studies of patients infected with clade C HIV have reported significant levels of cognitive impairmen...

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Publicat a:J Neurovirol
Autors principals: Paul, Robert H., Joska, John A., Woods, Carol, Seedat, Soraya, Engelbrecht, Susan, Hoare, Jacqueline, Heaps, Jodi, Valcour, Victor, Ances, Beau, Baker, Laurie M., Salminen, Lauren E., Stein, Dan J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268069/
https://ncbi.nlm.nih.gov/pubmed/25366660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-014-0293-z
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