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Regulation of TGF-β Family Signaling by Inhibitory Smads

Inhibitory Smads (I-Smads) have conserved carboxy-terminal MH2 domains but highly divergent amino-terminal regions when compared with receptor-regulated Smads (R-Smads) and common-partner Smads (co-Smads). Smad6 preferentially inhibits Smad signaling initiated by the bone morphogenetic protein (BMP)...

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Publicat a:Cold Spring Harb Perspect Biol
Autors principals: Miyazawa, Keiji, Miyazono, Kohei
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334261/
https://ncbi.nlm.nih.gov/pubmed/27920040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a022095
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