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The Cellular Origin and Evolution of Breast Cancer
In this review, we will discuss how the cell of origin may modulate breast cancer intratumoral heterogeneity (ITH) as well as the role of ITH in the evolution of cancer. The clonal evolution and the cancer stem cell (CSC) models, as well as a model that integrates clonal evolution with a CSC hierarc...
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| Publicat a: | Cold Spring Harb Perspect Med |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5334246/ https://ncbi.nlm.nih.gov/pubmed/28062556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a027128 |
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