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The Cellular Origin and Evolution of Breast Cancer

In this review, we will discuss how the cell of origin may modulate breast cancer intratumoral heterogeneity (ITH) as well as the role of ITH in the evolution of cancer. The clonal evolution and the cancer stem cell (CSC) models, as well as a model that integrates clonal evolution with a CSC hierarc...

詳細記述

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書誌詳細
出版年:Cold Spring Harb Perspect Med
主要な著者: Zhang, Mei, Lee, Adrian V., Rosen, Jeffrey M.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334246/
https://ncbi.nlm.nih.gov/pubmed/28062556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a027128
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