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Let-7 Status is Crucial for PARP1 Expression in HER2-overexpressing Breast Tumors
HER2+ breast tumors have been shown to express elevated levels of poly (ADP-ribose) polymerase 1 (PARP1) protein. Yet, the mechanism by which PARP1 is upregulated in HER2+ breast cancer is unknown. Here, knockdown of HER2 (ERBB2) in HER2+ breast cancer cells resulted in a reduction in PARP1 protein....
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| Publicado no: | Mol Cancer Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5334184/ https://ncbi.nlm.nih.gov/pubmed/28031413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0287-T |
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