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PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers
PURPOSE: Previous studies have shown that basal breast cancers, which may have an inherent “BRCAness” phenotype and sensitivity to inhibitors of poly (ADP-Ribose) polymerase (PARP), express elevated levels of PARP1. Our lab recently reported that HER2+ breast cancers also exhibit sensitivity to PARP...
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| 出版年: | Breast Cancer Res Treat |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4396624/ https://ncbi.nlm.nih.gov/pubmed/25833211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3359-6 |
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