Eltrombopag, a thrombopoietin mimetic, crosses the blood-brain-barrier and impairs iron-dependent hippocampal neuron dendrite development

BACKGROUND: Thrombocytopenia is common in sick neonates. Thrombopoietin mimetics (e.g., eltrombopag (ELT)) might provide an alternative therapy for selected neonates with severe and prolonged thrombocytopenia, and for infants and young children with different varieties of thrombocytopenia. However,...

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發表在:J Thromb Haemost
Main Authors: Bastian, Thomas W., Duck, Kari A., Michalopoulos, George C., Chen, Michael J., Liu, Zhi-Jian, Connor, James R., Lanier, Lorene M., Sola-Visner, Martha C., Georgieff, Michael K.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334144/
https://ncbi.nlm.nih.gov/pubmed/28005311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13602
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