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Eltrombopag, a thrombopoietin mimetic, crosses the blood-brain-barrier and impairs iron-dependent hippocampal neuron dendrite development

BACKGROUND: Thrombocytopenia is common in sick neonates. Thrombopoietin mimetics (e.g., eltrombopag (ELT)) might provide an alternative therapy for selected neonates with severe and prolonged thrombocytopenia, and for infants and young children with different varieties of thrombocytopenia. However,...

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Détails bibliographiques
Publié dans:J Thromb Haemost
Auteurs principaux: Bastian, Thomas W., Duck, Kari A., Michalopoulos, George C., Chen, Michael J., Liu, Zhi-Jian, Connor, James R., Lanier, Lorene M., Sola-Visner, Martha C., Georgieff, Michael K.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334144/
https://ncbi.nlm.nih.gov/pubmed/28005311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13602
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