Eltrombopag, a thrombopoietin mimetic, crosses the blood-brain-barrier and impairs iron-dependent hippocampal neuron dendrite development

BACKGROUND: Thrombocytopenia is common in sick neonates. Thrombopoietin mimetics (e.g., eltrombopag (ELT)) might provide an alternative therapy for selected neonates with severe and prolonged thrombocytopenia, and for infants and young children with different varieties of thrombocytopenia. However,...

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Vydáno v:J Thromb Haemost
Hlavní autoři: Bastian, Thomas W., Duck, Kari A., Michalopoulos, George C., Chen, Michael J., Liu, Zhi-Jian, Connor, James R., Lanier, Lorene M., Sola-Visner, Martha C., Georgieff, Michael K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334144/
https://ncbi.nlm.nih.gov/pubmed/28005311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13602
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