Effects of leukotriene D(4) nasal challenge on bronchial responsiveness and inflammation in asthmatic patients with allergic rhinitis

BACKGROUND: In asthmatic patients with allergic rhinitis (AR), increased cysteinyl leukotrienes (CysLTs) production in the secretion of nasal mucosa has been associated with greater bronchial hyperresponsiveness (BHR) after nasal allergen challenge. However, the role of CysLTs in eliciting BHR after...

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Bibliographic Details
Published in:J Thorac Dis
Main Authors: Zhu, Zheng, Xie, Yanqing, Guan, Weijie, Gao, Yi, Huang, Rongquan, Xia, Shu, Jian, Wenhua, Liang, Zhiyu, Zheng, Jinping
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334110/
https://ncbi.nlm.nih.gov/pubmed/28275474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2017.02.36
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