Effects of leukotriene D(4) nasal challenge on bronchial responsiveness and inflammation in asthmatic patients with allergic rhinitis

BACKGROUND: In asthmatic patients with allergic rhinitis (AR), increased cysteinyl leukotrienes (CysLTs) production in the secretion of nasal mucosa has been associated with greater bronchial hyperresponsiveness (BHR) after nasal allergen challenge. However, the role of CysLTs in eliciting BHR after...

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Detalhes bibliográficos
Publicado no:J Thorac Dis
Main Authors: Zhu, Zheng, Xie, Yanqing, Guan, Weijie, Gao, Yi, Huang, Rongquan, Xia, Shu, Jian, Wenhua, Liang, Zhiyu, Zheng, Jinping
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334110/
https://ncbi.nlm.nih.gov/pubmed/28275474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2017.02.36
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