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Effects of Aging and Oxidative Stress on Spermatozoa of Superoxide-Dismutase 1- and Catalase-Null Mice
Advanced paternal age is linked to complications in pregnancy and genetic diseases in offspring. Aging results in excess reactive oxygen species (ROS) and DNA damage in spermatozoa; this damage can be transmitted to progeny with detrimental consequences. Although there is a loss of antioxidants with...
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| Publié dans: | Biol Reprod |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for the Study of Reproduction, Inc.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333935/ https://ncbi.nlm.nih.gov/pubmed/27465136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.116.141671 |
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