Peptide amphiphile nanofiber hydrogel delivery of Sonic hedgehog protein to the cavernous nerve to promote regeneration and prevent erectile dysfunction

Erectile dysfunction (ED) has high impact on quality of life in prostatectomy, diabetic and aging patients. An underlying mechanism is cavernous nerve (CN) injury, which causes ED in up to 80% of prostatectomy patients. We examine how sonic hedgehog (SHH) treatment with innovative peptide amphiphile...

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Veröffentlicht in:Nanomedicine
Hauptverfasser: Choe, Shawn, Bond, Christopher W., Harrington, Daniel A., Stupp, Samuel I., McVary, Kevin T., Podlasek, Carol A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333775/
https://ncbi.nlm.nih.gov/pubmed/27609775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2016.08.032
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