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Peptide amphiphile nanofiber hydrogel delivery of Sonic hedgehog protein to the cavernous nerve to promote regeneration and prevent erectile dysfunction

Erectile dysfunction (ED) has high impact on quality of life in prostatectomy, diabetic and aging patients. An underlying mechanism is cavernous nerve (CN) injury, which causes ED in up to 80% of prostatectomy patients. We examine how sonic hedgehog (SHH) treatment with innovative peptide amphiphile...

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Détails bibliographiques
Publié dans:Nanomedicine
Auteurs principaux: Choe, Shawn, Bond, Christopher W., Harrington, Daniel A., Stupp, Samuel I., McVary, Kevin T., Podlasek, Carol A.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333775/
https://ncbi.nlm.nih.gov/pubmed/27609775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2016.08.032
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