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Both canonical and non-canonical NF-κB activation contribute to the proliferative response of the middle ear mucosa during bacterial infection

A major aspect of pathology in otitis media (OM), the most common childhood bacterial disease, is hyperplasia of the middle ear mucosa. Activation of innate immune receptors during OM leads to the activation of NF-κB, a pleiotropic transcription factor involved both in inflammation and tissue growth...

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Bibliographische Detailangaben
Veröffentlicht in:Innate Immun
Hauptverfasser: Cho, Chang Gun, Pak, Kwang, Webster, Nicholas, Kurabi, Arwa, Ryan, Allen F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333768/
https://ncbi.nlm.nih.gov/pubmed/27655045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425916668581
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