Specific patterns of oncogene activation in transplacentally induced tumors.
Transplacental exposure of rats to a single dose of the direct acting carcinogen methylnitrosourea (MNU) results in the induction of a variety of neoplasias of neuroectodermal, epithelial, and mesenchymal origin. Molecular analysis of the oncogenes present in these tumors revealed a striking degree...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1990
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53337/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2405388/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.2.718 |
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