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Specific patterns of oncogene activation in transplacentally induced tumors.

Transplacental exposure of rats to a single dose of the direct acting carcinogen methylnitrosourea (MNU) results in the induction of a variety of neoplasias of neuroectodermal, epithelial, and mesenchymal origin. Molecular analysis of the oncogenes present in these tumors revealed a striking degree...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sukumar, S, Barbacid, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53337/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2405388/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.2.718
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