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Strand-specific in vivo screen of cancer-associated miRNAs unveils a role for miR-21(*) in SCC progression

MicroRNAs play diverse roles in both normal and malignant stem cells. Focusing on miRs and/or miR(*)s abundant in squamous cell carcinoma (SCC) stem cells, we engineer an efficient, strand-specific expression library, and apply functional genomics screening in mice to identify which of 169 cancer-as...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Ge, Yejing, Zhang, Liang, Nikolova, Maria, Reva, Boris, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333577/
https://ncbi.nlm.nih.gov/pubmed/26619149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3275
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