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miR-125b can enhance skin tumor initiation and promote malignant progression by repressing differentiation and prolonging cell survival
Previously, we identified miR-125b as a key regulator of the undifferentiated state of hair follicle stem cells. Here, we show that in both mice and humans, miR-125b is abundantly expressed, particularly at early stages of malignant progression to squamous cell carcinoma (SCC), the second most preva...
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| Publicado no: | Genes Dev |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233245/ https://ncbi.nlm.nih.gov/pubmed/25403182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.248377.114 |
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