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Imatinib and its combination with 2,5-dimethyl-celecoxibinduces apoptosis of human HT-29 colorectal cancer cells

Mono-targeting by imatinib as a main antitumor agent does not always accomplish complete cancer suppression. 2,5-dimethyl-celecoxib (DMC) is a close structural analog of the selective cyclooxygenase-2 (COX-2) inhibitor, celecoxib, that lacks COX-2 inhibitory function. In this study, we aimed to show...

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Detalhes bibliográficos
Publicado no:Res Pharm Sci
Main Authors: Atari-Hajipirloo, Somayeh, Nikanfar, Saba, Heydari, Amir, Kheradmand, Fatemeh
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333482/
https://ncbi.nlm.nih.gov/pubmed/28255316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.199049
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