Imatinib alters cell viability but not growth factors levels in TM4 Sertoli cells

BACKGROUND: The anticancer agent imatinib (IM) is a small molecular analog of ATP that inhibits tyrosine kinase activity of platelet derived growth factors (PDGFs) and stem cell factor (SCF) receptor in cancer cells. However these factors have a key role in regulating growth and development of norma...

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Vydáno v:Int J Reprod Biomed
Hlavní autoři: Hashemnia, Seyyed Mohammad Reza, Atari-Hajipirloo, Somayeh, Roshan-Milani, Shiva, Valizadeh, Nasim, Mahabadi, Sonya, Kheradmand, Fatemeh
Médium: Artigo
Jazyk:Inglês
Vydáno: Research and Clinical Center for Infertility 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054294/
https://ncbi.nlm.nih.gov/pubmed/27738659
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