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Identification of somatic mutations using whole-exome sequencing in Korean patients with acute myeloid leukemia

BACKGROUND: Acute myeloid leukemia (AML) is a biologically and clinically heterogeneous cancer of the bone marrow that is characterized by the rapid growth of abnormal myeloid cells. METHODS: We performed a mutational analysis to identify AML somatic mutations using the whole-exome sequencing data o...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Heo, Seong Gu, Koh, Youngil, Kim, Jong Kwang, Jung, Jongsun, Kim, Hyung-Lae, Yoon, Sung-Soo, Park, Ji Wan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333433/
https://ncbi.nlm.nih.gov/pubmed/28249600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-017-0382-y
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