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Effects of Somatic Mutations Are Associated with SNP in the Progression of Individual Acute Myeloid Leukemia Patient: The Two-Hit Theory Explains Inherited Predisposition to Pathogenesis

This study evaluated the effects of somatic mutations and single nucleotide polymorphisms (SNPs) on disease progression and tried to verify the two-hit theory in cancer pathogenesis. To address this issue, SNP analysis was performed using the UCSC hg19 program in 10 acute myeloid leukemia patients (...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Park, Soyoung, Koh, Youngil, Yoon, Sung-Soo
פורמט: Artigo
שפה:Inglês
יצא לאור: Korea Genome Organization 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630383/
https://ncbi.nlm.nih.gov/pubmed/23613680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5808/GI.2013.11.1.34
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