Connecting genetic risk to disease end points through the human blood plasma proteome

Genome-wide association studies (GWAS) with intermediate phenotypes, like changes in metabolite and protein levels, provide functional evidence to map disease associations and translate them into clinical applications. However, although hundreds of genetic variants have been associated with complex...

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Publicado no:Nat Commun
Main Authors: Suhre, Karsten, Arnold, Matthias, Bhagwat, Aditya Mukund, Cotton, Richard J., Engelke, Rudolf, Raffler, Johannes, Sarwath, Hina, Thareja, Gaurav, Wahl, Annika, DeLisle, Robert Kirk, Gold, Larry, Pezer, Marija, Lauc, Gordan, El-Din Selim, Mohammed A., Mook-Kanamori, Dennis O., Al-Dous, Eman K., Mohamoud, Yasmin A., Malek, Joel, Strauch, Konstantin, Grallert, Harald, Peters, Annette, Kastenmüller, Gabi, Gieger, Christian, Graumann, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333359/
https://ncbi.nlm.nih.gov/pubmed/28240269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14357
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