Connecting genetic risk to disease end points through the human blood plasma proteome

Genome-wide association studies (GWAS) with intermediate phenotypes, like changes in metabolite and protein levels, provide functional evidence to map disease associations and translate them into clinical applications. However, although hundreds of genetic variants have been associated with complex...

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Pubblicato in:Nat Commun
Autori principali: Suhre, Karsten, Arnold, Matthias, Bhagwat, Aditya Mukund, Cotton, Richard J., Engelke, Rudolf, Raffler, Johannes, Sarwath, Hina, Thareja, Gaurav, Wahl, Annika, DeLisle, Robert Kirk, Gold, Larry, Pezer, Marija, Lauc, Gordan, El-Din Selim, Mohammed A., Mook-Kanamori, Dennis O., Al-Dous, Eman K., Mohamoud, Yasmin A., Malek, Joel, Strauch, Konstantin, Grallert, Harald, Peters, Annette, Kastenmüller, Gabi, Gieger, Christian, Graumann, Johannes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333359/
https://ncbi.nlm.nih.gov/pubmed/28240269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14357
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