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In silico evolution of the Drosophila gap gene regulatory sequence under elevated mutational pressure
BACKGROUND: Cis-regulatory sequences are often composed of many low-affinity transcription factor binding sites (TFBSs). Determining the evolutionary and functional importance of regulatory sequence composition is impeded without a detailed knowledge of the genotype-phenotype map. RESULTS: We simula...
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| Publicado no: | BMC Evol Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333172/ https://ncbi.nlm.nih.gov/pubmed/28251865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-016-0866-y |
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