Translating natural genetic variation to gene expression in a computational model of the Drosophila gap gene regulatory network

Annotating the genotype-phenotype relationship, and developing a proper quantitative description of the relationship, requires understanding the impact of natural genomic variation on gene expression. We apply a sequence-level model of gap gene expression in the early development of Drosophila to an...

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Veröffentlicht in:PLoS One
Hauptverfasser: Gursky, Vitaly V., Kozlov, Konstantin N., Kulakovskiy, Ivan V., Zubair, Asif, Marjoram, Paul, Lawrie, David S., Nuzhdin, Sergey V., Samsonova, Maria G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595321/
https://ncbi.nlm.nih.gov/pubmed/28898266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184657
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