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The Intra-S Checkpoint Responses to DNA Damage
Faithful duplication of the genome is a challenge because DNA is susceptible to damage by a number of intrinsic and extrinsic genotoxins, such as free radicals and UV light. Cells activate the intra-S checkpoint in response to damage during S phase to protect genomic integrity and ensure replication...
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| Publicado en: | Genes (Basel) |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333063/ https://ncbi.nlm.nih.gov/pubmed/28218681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8020074 |
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