PreC and C Regions of Woodchuck Hepatitis Virus Facilitate Persistent Expression of Surface Antigen of Chimeric WHV-HBV Virus in the Hydrodynamic Injection BALB/c Mouse Model

In the hydrodynamic injection (HI) BALB/c mouse model with the overlength viral genome, we have found that woodchuck hepatitis virus (WHV) could persist for a prolonged period of time (up to 45 weeks), while hepatitis B virus (HBV) was mostly cleared at week four. In this study, we constructed a ser...

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Gepubliceerd in:Viruses
Hoofdauteurs: Wu, Weimin, Liu, Yan, Lin, Yong, Pan, Danzhen, Yang, Dongliang, Lu, Mengji, Xu, Yang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332954/
https://ncbi.nlm.nih.gov/pubmed/28230775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9020035
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