Novel Woodchuck Hepatitis Virus (WHV) Transgene Mouse Models Show Sex-Dependent WHV Replicative Activity and Development of Spontaneous Immune Responses to WHV Proteins

The woodchuck model is an informative model for studies on hepadnaviral infection. In this study, woodchuck hepatitis virus (WHV) transgenic (Tg) mouse models based on C57BL/6 mice were established to study the pathogenesis associated with hepadnaviral infection. Two lineages of WHV Tg mice, harbori...

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Autors principals: Meng, Zhongji, Ma, Zhiyong, Zhang, Ejuan, Kosinska, Anna D., Liu, Jia, Zhang, Xiaoyong, Zhou, Tianlun, Wu, Jun, Dahmen, Uta, Dirsch, Olaf, Yang, Dongliang, Roggendorf, Michael, Lu, Mengji
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911616/
https://ncbi.nlm.nih.gov/pubmed/24257601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02086-13
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