Novel Woodchuck Hepatitis Virus (WHV) Transgene Mouse Models Show Sex-Dependent WHV Replicative Activity and Development of Spontaneous Immune Responses to WHV Proteins

The woodchuck model is an informative model for studies on hepadnaviral infection. In this study, woodchuck hepatitis virus (WHV) transgenic (Tg) mouse models based on C57BL/6 mice were established to study the pathogenesis associated with hepadnaviral infection. Two lineages of WHV Tg mice, harbori...

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Bibliografiset tiedot
Päätekijät: Meng, Zhongji, Ma, Zhiyong, Zhang, Ejuan, Kosinska, Anna D., Liu, Jia, Zhang, Xiaoyong, Zhou, Tianlun, Wu, Jun, Dahmen, Uta, Dirsch, Olaf, Yang, Dongliang, Roggendorf, Michael, Lu, Mengji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Pathogenesis and Immunity
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911616/
https://ncbi.nlm.nih.gov/pubmed/24257601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02086-13
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