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Heightened extended amygdala metabolism following threat characterizes the early phenotypic risk to develop anxiety-related psychopathology

Children with an anxious temperament (AT) are prone to heightened shyness and behavioral inhibition (BI). When chronic and extreme, this anxious, inhibited phenotype is an important early-life risk factor for the development of anxiety disorders, depression, and co-morbid substance abuse. Individual...

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Détails bibliographiques
Publié dans:Mol Psychiatry
Auteurs principaux: Shackman, Alexander J., Fox, Andrew S., Oler, Jonathan A., Shelton, Steven E., Oakes, Terrence R., Davidson, Richard J., Kalin, Ned H.
Format: Artigo
Langue:Inglês
Publié: 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332536/
https://ncbi.nlm.nih.gov/pubmed/27573879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.132
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