Silencing Vimentin Expression Decreases Pulmonary Metastases in a Pre-Diabetic Mouse Model of Mammary Tumor Progression

Increased breast cancer risk and mortality has been associated with obesity and Type 2 diabetes (T2D). Hyperinsulinemia, a key factor in obesity, pre-diabetes and T2D, has been associated with decreased breast cancer survival. In the current study, a mouse model of pre-diabetes (MKR mouse) was used...

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Bibliographic Details
Published in:Oncogene
Main Authors: Zelenko, Zara, Gallagher, Emily J., Tobin-Hess, Aviva, Belardi, Valentina, Rostoker, Ran, Blank, Jeffery, Dina, Yemisi, LeRoith, Derek
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332535/
https://ncbi.nlm.nih.gov/pubmed/27568979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.305
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