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Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies

A major challenge in anticancer treatment is the pre-existence or emergence of resistance to therapy. AXL and MER are two members of the TAM (TYRO3-AXL-MER) family of receptor tyrosine kinases, which, when activated, can regulate tumor cell survival, proliferation, migration and invasion, angiogenes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Oncol Rep
Hauptverfasser: Schoumacher, Marie, Burbridge, Mike
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332501/
https://ncbi.nlm.nih.gov/pubmed/28251492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-017-0579-4
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